Banca de DEFESA: DINALIA CAROLINA LOPES PACHECO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE : DINALIA CAROLINA LOPES PACHECO
DATA : 24/02/2021
HORA: 14:30
LOCAL: Ambiente Virtual link: https://meet.google.com/myd-mbdn-uzh
TÍTULO:

NEURODEGENERATIVE DISEASES IN THE CITY OF ITAITUBA - PARÁ: AN EPIDEMIOLOGICAL ANALYSIS

PALAVRAS-CHAVES:

Neurodegenerative diseases. Mercury. Seniors. Itaituba

PÁGINAS: 172
GRANDE ÁREA: Ciências da Saúde
ÁREA: Saúde Coletiva
SUBÁREA: Epidemiologia
RESUMO:

Neurodegenerative diseases (ND) are a serious health problem, as not yet all of their causes are known, but it is known that among some causes, environmental, physical-chemical, biological, genetic factors may be related. Thus, the objective of this study is to verify the occurrence and analysis of the epidemiological profile of occurences of neurodegenerative diseases in the municipality of Itaituba (Pará), and to to investigate a possible correlation between the occurrence of neurodegenerative diseases and mercury levels in groups of patients with and without these diseases in the municipality of Itaituba-PA. This work describes the occurrence of ND of Alzheimer, Parkinson and Amyotrophic Lateral Sclerosis, found in the urban area of the municipality of Itaituba - Pará; to know the epidemiological profile of patients with neurodegenerative diseases and non-carriers; in addition to quantifying the mercury levels of biological plasma samples in individuals with neurodegenerative diseases and non-carriers. Thus, it was developed through the application of a semi-structured form, and collection of biological samples from 29 patients with ND, and 29 volunteers without ND who were 60 years old or more, during the period from February to August of 2020. For the analysis of the data of this research, descriptive statistics was used, with the correlation of the data and multivariate analysis. This study made it possible to delineate the epidemiological profile of the patients analyzed, with a main focus on the presence of neurodegenerative diseases and the conditions that they add up to their occurrence. Thus, 17 confirmed cases of Parkinson's disease were identified, 12 cases of Alzheimer's disease and none of the patients with Amyotrophic Lateral Sclerosis. In this research, there was a higher average in some variables for the group with ND, and among these, the highest average results for the total mercury concentrations in plasma samples stand out. So, it was found by this study, varied factors that goes beyond heredity, as a contributing component for the occurrence of ND, thus, there was the presence of occupational elements, and lifestyle factors. However, in this research, there was no strong relationship between the levels of mercury found with occupational activity in mining and neurodegenerative diseases. However, it was possible to associate the levels of mercury found with the presence of ND. Therefore, this research has presented important results that aim to contribute to improve the quality of life of the local population.

MEMBROS DA BANCA:
Presidente - 1562643 - MAXWELL BARBOSA DE SANTANA
Interno - 2143267 - JOSE MAX BARBOSA DE OLIVEIRA JUNIOR
Externo ao Programa - 1190556 - RICARDO BEZERRA DE OLIVEIRA
Externa ao Programa - 2383596 - HELOISA DO NASCIMENTO DE MOURA MENESES