Banca de DEFESA: KARINE RODRIGUES DO NASCIMENTO CHAVES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : KARINE RODRIGUES DO NASCIMENTO CHAVES
DATE: 02/04/2024
TIME: 14:00
LOCAL: Sala 327, BMT1
TITLE:

CHEMICAL CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF COMPOUNDS OBTAINED FROM ACTINOBACTERIA ISOLATED FROM CARBONATE ROCKS IN THE AMAZON

KEY WORDS:

Streptomyces. Bioinnovation. Biotechnological potential.

PAGES: 45
BIG AREA: Ciências Biológicas
AREA: Microbiologia
SUBÁREA: Microbiologia Aplicada
SPECIALTY: Microbiologia Industrial e de Fermentação
SUMMARY:

Bioprospecting represents a multidisciplinary field focused on the discovery and improvement
of new products, processes, and applications from natural resources. This type of research has
been ongoing since the 20th century, with Actinobacteria standing out as a promising source of
biotechnological potential. However, despite the economic and biotechnological benefits
inherent to Actinobacteria, the Amazon region remains relatively underexplored in this regard.
Therefore, the present study aims to investigate the bioprospecting of Actinobacteria isolated
from carbonate rocks in the Amazon to explore their antimicrobial, antioxidant, cytotoxic, and
antitumor activities. Morphological and biochemical characterization, 16S rRNA gene
sequencing, antagonism testing, isolation of antimicrobial secondary metabolites, analysis of
gene cluster biosynthesis of secondary metabolites in actinobacteria, evaluation of minimum
inhibitory concentration, minimum bactericidal and fungicidal concentration of the crude
extract, and chemical characterization of the crude extract will be conducted.

COMMITTEE MEMBERS:
Presidente - 1833953 - SILVIA KATRINE RABELO DA SILVA
Interna - ***.421.662-** - SANDRA LAYSE FERREIRA SARRAZIN - UFPA
Externa à Instituição - SARA FREITAS DE SOUSA RAMOS
Externa à Instituição - ISABELLA CRISTHINA GONÇALVES COSTA