Banca de QUALIFICAÇÃO: MAYARA RENATA LIMA MOTA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : MAYARA RENATA LIMA MOTA
DATE: 06/08/2024
TIME: 09:00
LOCAL: Laboratório de Biotecnologia de Plantas Medicinais
TITLE:

OF THE STUDY ON THE ANTI-INFLAMMATORY POTENTIAL OF Protium heptaphyllum ESSENTIAL OIL IN MUSCLE STRAIN in  Rattus norvegicus albinus

KEY WORDS:

Protium heptaphyllum; Anti-Inflammatory;  Muscle strain

PAGES: 30
BIG AREA: Ciências Biológicas
AREA: Biotecnologia
SUMMARY:

The muscle strain, considered an indirect injury, is characterized by the stretching of fibers beyond physiological limits. The use of medicinal plants, especially those that produce essential oils, presents a promising approach to assist in the muscle repair process. In this context, the species Protium heptaphyllum, commonly found in the Amazon region, serves as a complementary phytotherapeutic treatment due to its anti-inflammatory properties. Interestingly, it is relatively underutilized for this type of injury. Therefore, this study aims to evaluate the anti-inflammatory potential of Protium Heptaphyllum essential oil in muscle strain in Rattus norvegicus albinus. The research will be conducted through an experimental approach, involving four experimental groups, each receiving a specific treatment. Muscle injury will be induced using a device previously described in the literature. To achieve the research objective, the chemical characterization of Protium Heptaphyllum essential oil will be performed using gas chromatography coupled with mass spectrometry, a technique used to identify hundreds of components in natural and biological systems. Additionally, histological analysis will explore muscle-related features, including the presence of inflammatory cells, crust formation, and angiogenesis. Furthermore, biochemical analysis will assess the blood markers Aspartate Aminotransferase (AST) and Creatine Kinase (CK), which indicate muscle injury.

COMMITTEE MEMBERS:
Presidente - 1776289 - ELAINE CRISTINA PACHECO DE OLIVEIRA
Interno - 2383549 - GUSTAVO DA SILVA CLAUDIANO
Externa à Instituição - JOSIANE ELIZABETH ALMEIDA E SILVA